QOL-27. Sociocultural variables have a major impact on participation in patients treated for pediatric posterior fossa tumors

Abstract OBJECTIVE: This study investigates the extent of participation barriers in patients with pediatric posterior fossa tumors (PFTs) at long-term follow-up. While most studies focus on pathobiological variables that promote occurrence adverse late effects, present analysis aims to investigate importance environmental variables. METHOD: Ten years after tumor diagnosis, 42 (mean age: 17 years) treated our neuro-oncology unit were assessed for school and social difficulties using a questionnaire developed within framework this study. Participation assumed if and/or their parents reported or peers. The children adolescents classified into groups adequate limited participation. Potential (treatment type, hydrocephalus, recurrence, gender, age seizures, cerebellar mutism) risk factors (parental maternal education, siblings, primary language, discrepancies between personal values, regular physical activity, private housing) identified examined see differed amount factors. RESULTS: Almost decade treatment, two thirds had difficulties. Not only (type mutism seizures), but also (low education level, main language other than German, irregular activity) associated These discriminated significantly without barriers. CONCLUSION: PFT are frequent. In addition variables, play an important role limiting underlines fact sole consideration pathobiology is not sufficient when examining effects. adoption biopsychosocial perspectives future inevitable.